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Description

Metabolic outcomes of ABHD11 inhibition in CD8 + T cells Metabolism is markedly different between immortalized cancer cells and primary cells, and while the major effect of ABHD11 inhibition in HeLa cells was on 2-OG metabolism and 2-OGDD activity, the downstream consequences of perturbing this glutaryllipoyl pathway in primary cells may differ from immortalized cancer cells

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Akshay V

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A., Foitzik-Lau, K., Goffin, V., Ramot, Y

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This is also where caution matters most

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