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Higher nicotine levels pose a threat to youth and young adult users Average nicotine strength increased in e-cigarettes with flavors that were classified as menthol, fruit, candy or sweet, tobacco, and beverage flavor (e.g., lemonade or soda)

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3.2.3 Influence on cardiovascular biomarkers Acute effects on biomarkers across five studies involving healthy populations with a history of smoking, including a randomized crossover study between tobacco smokers and non-smokers, demonstrated that active e-cigarette use in smokers and passive use in healthy individuals did not affect blood count markers