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The symptoms of a B-12 deficiency include numbness or tingling of the extremities, fatigue, weakness, anemia, swollen tongue, jaundice, difficulty walking, cognitive difficulties, memory loss and paranoia

Our results provided evidence that inhibition of protein translation alone is sufficient to rescue both mTORC1 signaling and the ISR, suggesting its major role in the regulation of amino acid sensing pathways in HepG2 cells

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