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Mutations caused by direct DNA damage from carcinogens in tobacco were seen mainly in organs that come into direct contact with inhaled smoke, says Professor David Phillips, an author on the paper

But smokers reach menopause an average of 1 1/2 years earlier than women who don't smoke

After 1 Year of Smoking Structural Changes Begin Chest CT and HRCT scans of early smokers often show : Airway thickening Mucus gland enlargement Early emphysema-like changes Functional Impairment A study by the European Respiratory Society shows that even 12 months of smoking causes: 510% reduction in lung function Reduced capacity for pollutant clearance Increased incidence of cough, colds, and allergies After 5 Years of Smoking Lung damage, by this stage, has become more pronounced and is visible on imaging

43 A very large US study published in 2020 similarly found surprisingly high levels of risk for those smoking five or fewer cigarettes per day