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Description

In glucocorticoid-induced atrophy models (dexamethasone 1mg/kg/day for 7 days in rodents), IGF-1 LR3 (0.5-1mg/kg/day) reduced Atrogin-1 by 42-52% and preserved myofibre cross-sectional area (H&E gastrocnemius CSA 18% vs dexamethasone alone vs 6% with IGF-1 LR3 co-treatment)

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