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doi: 10.1146/annurev-publhealth-040617-013638

They're designed to mimic a hormone that signals to the brain when a person is full and promotes the release of insulin, a hormone that stops blood sugar from getting too high

How Wegovy Compares to Other GLP-1 Options in Michigan | Medication | Active ingredient | Monthly list price (2026) | Indication | |---|---|---|---| | Wegovy 2.4 mg | Semaglutide | $1,349 | Chronic weight management | | Ozempic 2 mg | Semaglutide | $935 | Type 2 diabetes (off-label for weight) | | Mounjaro 15 mg | Tirzepatide | $1,023 | Type 2 diabetes (off-label for weight) | | Zepbound 15 mg | Tirzepatide | $1,059 | Chronic weight management | | Saxenda | Liraglutide 3 mg | $1,415 | Chronic weight management | Ozempic and Mounjaro are approved for type 2 diabetes, not chronic weight management

Diabetes Obes Metab 2018;20:22102219