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Table 3 summarizes the PIONEER trial programmes [35,36,37,38,39,40,41,42,43,44]

[Search terms -- rybelsus OR ((semaglutide OR NN9535 OR NN 9535 OR NNC 0113-0217) AND (oral OR mouth OR orally)) | diabetes Search dates: December 14, 2020 December 18, 2020 Keywords: rybelsus OR ((semaglutide OR NN9535 OR NN 9535 OR NNC 0113-0217) AND (oral OR mouth OR orally Limits: Humans Updated: Search updated before the CADTH Canadian Drug Expert Committee (CDEC) meeting Relevant websites from the following sections of the CADTH grey literature checklist Grey Matters: A Practical Tool For Searching Health-Related Grey Literature ( were searched: Health Technology Assessment Agencies Health Economics Clinical Practice Guidelines Drug and Device Regulatory Approvals Advisories and Warnings Drug Class Reviews Clinical Trials Registries Databases (free) Health Statistics Internet Search Note that this appendix has not been copy-edited

Dietary Recommendations for the Management of Gastrointestinal Symptoms in Patients Treated with GLP-1 Receptor Agonist

Ask if youll need to try other medications or weight management strategies before semaglutide will be covered