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Pharmacological activation of GPR68 with MS48107 or the clinically approved benzodiazepine Lorazepam robustly reversed ferroptosis by enhancing Akt phosphorylation and Nrf2 nuclear translocation

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While the researchers adjusted for many risk factors, including age, sex, race/ethnicity, smoking, and physical activity, there is not explicit statement in regards to the individuals body fat percentage or body mass index (BMI) and its correlation to increased risk of ASCVD