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As new research, observations, and ideas are presented, this information MUST be used to challenge previously held beliefs to assure that they are still sound

It can be weakened by things like stress, illness, a poor diet, insufficient sleep or lack of activity

Yet, despite their ability to sustain energetics and functionality in critical tissues, animals subjected to this fasting-refeeding cycle displayed lasting physiological changes, including a reduction in body size that persisted well into later life (Supplementary Fig

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