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This typically includes measurement of IGF-1 and, where indicated, dynamic GH stimulation testing (such as an insulin tolerance test or glucagon stimulation test) and pituitary imaging

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2010 in J Clin Endocrinol Metab pooled the original Phase 3 with the confirmatory NCT00435136 (combined n = 816) and reported sustained visceral-adipose-tissue reduction over 52 weeks alongside broadly stable glucose parameters [7]