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Solis et al, 2010) and decreased response to various classes of cancer therapeutics (Gadgeel et al, 2020

Most common side effects of topiramate: The common side effects of topiramate include tingling in the arms and legs (paresthesia), drowsiness or fatigue, dizziness, nausea, difficulty with memory or concentration, and changes in taste

It is also hydrophilic, suggesting problems in transporting it across the BBB (unlike PBN) (Tanguy et al., 2006) and increased the lifespan and neuroprotective action in a Philodina acuticornis (a species of freshwater bdelloid rotifers) model (Poeggeler et al., 2005)

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