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the related published evidence on Epithalon-specific effects on melatonin comes from animal models

A multi-center phase-II clinical trial, started a few years ago to investigate the biological and clinical effects of rapamycin in people with ALS, is currently underway and will provide important information for further potential trials [312], thus opening new therapeutic perspectives for ALS

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These tiny channels trigger the natural production of collagen and elastin essential proteins that repair and renew the skin