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The study, published in The Journal of Neuroscience, used a new way of analyzing PET (positron emission tomography) scans to create movies of the dopamine response during smoking to demonstrate for the first time that smoking-induced dopamine activation occurs in a different brain region and much faster in nicotine-dependent men than women

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Mendelson JH, Sholar MB, Goletiani NV, Siegel AJ, Mello NK (2005)