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Those with certain types of asthma , as it might worsen symptoms

[DOI] [PMC free article] [PubMed] [Google Scholar] 296.Allirot X, da Quinta N, Chokupermal K, Urdaneta E

The role of HOTYR as a chemo-preventive anti-carcinogenic compound has received attention in human carcinoma cells in many in vitro studies showing significant effects in several cancer cell lines as main responsible compound, either alone or in a synergistic manner (82), arresting the cell cycle at any of its phases, producing differentiation, apoptosis, or preventing DNA from oxidative stress (Table 2)

Another meta-analysis including children ages 6-17 with obesity, type 2 diabetes, or prediabetes found that GLP-1s significantly reduced A1C and weight compared to placebo