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Also in the DURATION trial, exenatide weekly had beneficial reductions of -3 to -5mm Hg in systolic blood pressure 6

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Contact your doctor immediately if you experience: Severe or persistent headaches Blurred vision or confusion Dizziness or fainting Nausea and vomiting that prevent hydration Signs of an allergic reaction (rash, swelling, or difficulty breathing) These could indicate more serious side effects of semaglutide or other potential complications requiring professional medical advice