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Low arginine appears to play a role in the pathogenesis of a number of varied diseases , including cardiovascular disease, acute asthma, pulmonary hypertension, cystic fibrosis, sickle cell disease, trauma, and certain cancers, among others
Consent for publication Informed consent was obtained from all individuals included in the study
In asthmatic immune cells (e.g., Th17 cells), Golgi fragmentation (induced by IL-17A) impairs ACSL4 trafficking to the ER, leading to cytosolic ACSL4 accumulation (110)
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