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These two nearly identical FBF proteins are largely redundant: fbf-1 and fbf-2 single mutants are both self-fertile with germlines organized as in wild-type

Among four flavonoids that were isolated from Apocynum venetum leaf, quercetin3-O-D-glucoside also showed anti-depressive activity with both gross changes (reduced immobility time) and biochemical alterations such as increased NE, DA, and 5-HT and reduced 5-HT metabolism (Yan et al., 2015)