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Downstream metabolic improvements changes in cortisol, insulin sensitivity, or body composition require longer windows of 612 weeks, and depend substantially on whether DSIP is used as part of a broader supervised metabolic protocol rather than in isolation

Research shows that getting multiple NAD+ treatments over several days gives the best results

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We mention this not to claim GHK-Cu is "better" than retinol - it isn't a fair comparison given the difference in research depth - but because it suggests the ingredient is doing something real at the structural level when formulated and applied thoughtfully