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Male knockouts exhibited increased anxiety-like behavior in the open field, elevated plus maze, and light-dark box tests, suggesting that the absence of GHR signaling in somatostatin cells leads to an anxiogenic phenotype in male mice, but not in females (74) (Figure 2)

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Influence of aging on the acute depletion of reduced glutathione induced by electrophilic agents

Growth hormone is a counter-regulatory hormone: it opposes insulin and can raise blood glucose and reduce insulin sensitivity