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Side effects are uncommon and usually mild: Soreness or redness at the injection site Mild digestive upset Allergic reactions, which are rare Because a shot is an injection, it should always be given by a trained provider

Many people with a deficiency describe deep fatigue, including an "afternoon crash." With infrequent dosing, blood levels can peak and then taper before the next visit

Im not saying any of this to scare you or to concern you, but to simply bring to your attention that vitamin B12 deficiency is a big deal

IV and short-duration oral trials METAOD001-004 enrolled smaller groups of healthy or obese men with single doses or 1-week dosing across IV (25-400 mcg/kg) and oral (9-54 mg) routes