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P-nitroaniline (Sigma-Aldrich, 185310) was used to generate a standard curve (040 nmoles) for the calculation of GGT activity

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Frequency of administration In the case wherein the patient's condition does not improve, upon the doctor's discretion the administration of the compounds is administered chronically, that is, for an extended period of time, including throughout the duration of the patient's life in order to ameliorate or otherwise control or limit the symptoms of the patient's disease or condition