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The Bottom Line GHK-Cu is a naturally occurring copper tripeptide that stimulates collagen synthesis at picomolar concentrations, modulates over 4,000 genes, and has shown measurable wrinkle reduction and collagen improvement in clinical studies

Blood glucose levels, HbA1c levels, weight changes, and any adverse reactions should be closely monitored

By Sabina Paglialunga, PhD & Aernout van Haarst, PhD Senior Directors Scientific Affairs Glucagon-Like Peptide-1 (GLP-1) receptor agonists first came to the market in 2005 as a type 2 diabetes mellitus treatment, and they have been making headlines again for their weight reduction effects

Dose limitation: There may be a practical ceiling on how much peptide you can deliver effectively via a nasal spray without irritation or escape (e.g., dripping into the throat)