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Clinical Evidence Clinical Trials for retatrutide demonstrate powerful appetite suppression in adults with obesity or overweight

In one study of the Novartis global safety database, there were 292 pregnancies with maternal ( n = 238) or paternal ( n = 54) exposure to secukinumab during pregnancy, with 153 known pregnancy outcomes

If no, go to step ii

For tirzepatide (Zepbound) Jastreboff and colleagues reported in the New England Journal of Medicine in 2022 that at maximal doses, the percent of individuals reporting side effects were as follows: Nausea 31.0% Diarrhea 23.0% Vomiting 12.2% Constipation 11.7% Bettge and colleagues conducted a study published in Diabetes, Obesity, and Metabolism in 2017 that showed that individuals who were taking metformin while taking a GLP-1 were more likely to have side effects, especially nausea and vomiting