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This research provides additional evidence to suggest that discontinuing GLP-1 agonists at least 14 days before total joint replacement surgery is optimal to reduce the risk of delayed emergence from anesthesia, aspiration events, aspiration pneumonitis and conversion to intubation, said John R

Ultimately, the cell swells and ruptures and the membrane potential are disturbed, culminating in necrotic cell death (Zhang et al., 2018c

The commentary, Unintended Consequences of Glucagon-like Peptide-1 Receptor Agonists Medication in Children and Adolescents A Call to Action, was published as a perspective in the Journal of Clinical and Translational Science

Some patients experience constipation due to prolonged transit time, while others may develop diarrhea, possibly related to changes in gut motility patterns or alterations in intestinal fluid handling