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After methyl transfer, SAM is converted to S-adenosylhomocysteine (SAH) that may undergo hydrolysis to homocysteine and adenosine

Graphical Abstract Similar content being viewed by others Introduction Myelodysplastic syndromes (MDS) is a group of myeloid neoplasms characterized by clonal proliferation of hematopoietic stem cells, myeloid cell dysplasia, ineffective hematopoiesis, cytopenia, and high risk of progression to acute myeloid leukemia (AML) [1]

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They might also acquire traits that are required to overtake host tissue