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Most people assume oral GLP-1 should be the cheaper option
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Research on subcutaneous peptide pharmacokinetics demonstrates that absorption from the abdomen is approximately 28% higher in peak concentration compared to thigh injections, with the time to peak concentration occurring more than twice as fast
Notably, metformin itself can impair B12 absorption, which makes the B12 in compounded semaglutide even more valuable for patients on both medications
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