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Description

Diagnostic and prognostic performance of neurofilaments in ALS

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Key points Vascular damage in chronic kidney disease (CKD) increases the risk of stroke and cognitive impairment, with faster CKD progression linked to cerebral damage, subcortical infarcts and bloodbrain barrier disruption

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The percentage of participants who failed to follow-up was less than 15 percent in eight trials, and two trials (Jamilian et al., 2017

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Adding complexity without a stable foundation often reduces clarity and may not improve outcomes

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