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GLP-1RAs and SGLT2 inhibitors also have pleiotropic effects, including blood glucose-dependent and -independent mechanisms, effects on the reninangiotensinaldosterone system and favourable effects on left ventricular and renal functions [35, 36]

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The dyes absorption in the therapeutic window (600950 nm) makes it effective for light-based applications using red or polychromatic sources (Tardivo et al