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Tolerability, pharmacokinetics and pharmacodynamics of the once-daily human GLP-1 analog liraglutide in Japanese healthy subjects: a randomized, double-blind, placebo-controlled dose-escalation study

Scarano A, Iezzi G, Petrone G, Orsini G, Degidi M, Strocchi R, et al

Notably, the bell-shaped doseresponse profiles seen in this Met dimerization assay with both dimeric macrocycles and hHGF (Supplementary Fig