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These decreases in body weight were not without costs, as semaglutide frequently caused gastrointestinal related side effects in patients

Antisera , , , glicentin ,oxyntomodulin -proglucagon 1-61 (Baldissera -Holst -Diabetologia 1986),

The body weight of rats in OA + liraglutide had no significant change when compared with OA + saline group before treatment with liraglutide ( P = 0.9310)

This heterogeneity may stem from differences in intervention duration, baseline health conditions, as well as the varying severity of depression and anxiety across study populations, which limited our ability to perform subgroup analyses based on baseline disease severity