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APX, which is the first enzyme of the cycle, detoxifies H 2 O 2 by bringing about the peroxidation of AsA and yielding monodehydroascorbate radical (MDHA)

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Striatum D3R D3R expressed on striatal neurons can raise dopamine concentration, decrease -Syn accumulation, enhance secretion of BDNF, ameliorate neuroinflammation, alleviate oxidative stress, and promote neurogenesis in the nigrostriatal pathway