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In a statement to the Chronicle, an Empower spokesperson emphasized that compounded medications are not prescribed simply because of price. A clinician may prescribe a compounded formulation because a patient needs a specific dose, concentration or delivery method that is not commercially available or not appropriate for that patient, the spokesperson said

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Additionally, both tirzepatide and berberine can cause gastrointestinal side effects including nausea, diarrhea, and abdominal discomfort, which may be additive when used together

Lassailly G, Caiazzo R, Ntandja-Wandji LC, Gnemmi V, Baud G, Verkindt H, et al