pioneer 4 semaglutide Efficacy and safety of oral vs sitagliptin in a predominantly Chinese population with type 2 diabetes uncontrolled with metformin: 12, a double-blind, Phase IIIa, randomised trial | Diabetologia Oral semaglutide versus subcutaneous liraglutide

10.1001/jama.2018.18269 Summary Keywords acarbose, dipeptidyl peptidase-4 inhibitors, glucose-lowering efficacy, network meta-analysis, randomized controlled trials, tolerability and safety issue, type 2 diabetes, weight-loss effect Citation Zhang F, Xu S, Tang L, Pan X and Tong N (2020) Acarbose With Comparable Glucose-Lowering but Superior Weight-Loss Efficacy to Dipeptidyl Peptidase-4 Inhibitors: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials

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Generic manufacturers must complete FDA approval processes, including demonstrating bioequivalence to the original drug