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Because pKa influences: Stability Reactivity Antioxidant capacity Glutathiones thiol group (from cysteine) is crucial for neutralizing free radicals

Medical studies suggest that glutathione levels may naturally decline with age, and various factors, including diet, lifestyle, and environmental exposures, may influence the body's glutathione production and utilization

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Laboratory investigations demonstrate that GHK-Cu exhibits a copper binding affinity (log K = 16.1) that positions it perfectly within the physiological copper transport hierarchystronger than albumin but weaker than ceruloplasminenabling controlled copper transfer to cellular targets