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This commonly includes lifelong treatment for pernicious anaemia, managing severe B12 deficiency with neurological symptoms to prevent further damage, and for individuals post-gastric surgery due to impaired absorption

The 50 mg vial is reconstituted with 2 mL of bacteriostatic water to achieve a 25 mg/mL concentration (0.25 mg per unit)

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The PROactive 294 trial showed that pioglitazone, compared with a placebo, reduced the risk of composite outcomes (all-cause mortality, nonfatal MI and stroke) by 16% in diabetic patients with established ASCVD