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Donald Hensrud, an associate professor of nutrition and preventive medicine at Mayo Clinic and author of The Mayo Clinic Diet, emphasizes, "The FDA approved GLP-1 medications for weight loss as part of a weight-management program: they were never designed to go it alone." While the ease of weight loss associated with GLP-1s is pervasive in advertising and social media, Mayo Clinic's Tara Schmidt, Lead Dietitian for the Mayo Clinic Diet, warns of the potential risks when not incorporating an online support program that puts quality nutrition first

The effect becomes more pronounced as the dose increases through the titration schedule

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