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However, the racemization of D-carnitine is difficult, and it cannot be recovered, requiring a breakthrough for industrial-scale production

doi: 10.1146/annurev-biochem-051710-134100 203 ShulhaH

But there are times where the body cannot keep up with the demand or is using it faster than it can be made

Although this was an ingenious approach, allosterically affecting the conformation of double-stranded DNA to prevent the AR DBD from binding has limited clinical applicability