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Before reconstitution (powder): Refrigerate at 36-46F (2-8C) Shelf life: 12-24 months Can handle short periods at room temp during shipping After reconstitution (liquid): Must refrigerate at 36-46F Shelf life: 28 days with bacteriostatic water Never freeze (destroys peptide structure) Label with date reconstituted Signs your BPC-157 has degraded: Solution becomes cloudy Visible particles or flakes Yellow or brown discoloration Unusual smell If you see any of these, discard the vial