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Reported side effects The side effects reported in trials and research protocols tend to be mild and transient: Common: Injection site reactions: redness, swelling, mild irritation at the injection location Headache: reported in some subjects, typically mild and temporary Mild gastrointestinal discomfort: occasional reports of nausea or upset stomach Less common: Temporary dizziness Slight increases in heart rate Minor liver enzyme elevations in some subjects These effects, when they occur, generally resolve without intervention and don't require discontinuation

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We also observed an increase in the 18 kDa translocator protein TSPO, which is a mitochondrial cholesterol-binding protein and upregulated in microglia during inflammatory activation associated with neurodegeneration (Fig

T., Vranje, D., Vukojevi, J., Tufan, M., Seiwerth, S., Sikiric, P