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This article covers the specific biological mechanisms that create uncertainty, the animal model findings that drive current washout recommendations, and the research design protocols labs use when pregnancy becomes a variable in peptide studies

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Wiviott SD, Raz I, Bonaca MP, Mosenzon O, Kato ET, Cahn A, Silverman MG, Zelniker TA, Kuder JF, Murphy SA, Bhatt DL, Leiter LA, McGuire DK, Wilding JPH, Ruff CT, Gause-Nilsson IAM, Fredriksson M, Johansson PA, Langkilde A-M, DECLARETIMI 58 Investigators (2019) Dapagliflozin and cardiovascular outcomes in type 2 diabetes